MolNFT v1 · #78510 · protein
Crystal structure of a leucine-rich repeat protein (BT_1240) from bacteroides thetaiotaomicron vpi-5482 at 1.99 a resolution
3SB4 · Hypothetical leucine rich repeat protein: “Crystal structure of a leucine-rich repeat protein (BT_1240) from bacteroides thetaiotaomicron vpi-5482 at…”. X-ray diffraction, 3 pockets (best druggability 0.71). MolNFT v1 #78510 on…
- PDB
- 3SB4
- Type
- protein
- Length
- 657 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hypothetical leucine rich repeat protein
- UniProt
- Q8A8C7
- Pockets
- 3 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 14% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hypothetical leucine rich repeat protein | protein | 329 | 14% helix, 30% strand | Q8A8C7 |
| B | Hypothetical leucine rich repeat protein | protein | 328 | 14% helix, 30% strand | Q8A8C7 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 633 | 0.71 | 0.79 | 89 | GOL |
| 2 | 288 | 0.59 | 0.78 | 34 | GOL |
| 3 | 202 | 0.53 | 0.78 | 33 | GOL |
Interfaces
1 interface between chains.
- A–B · 1015 Ų buried · 14 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 16 modified (engineered).
Compared structures
- 3SB4 · Crystal structure of a leucine-rich repeat protein (BT_1240) from Bacteroides… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8A8C7
- Elsewhere: RCSB PDB 3SB4 · PDBe 3SB4 · UniProt Q8A8C7
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