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MolNFT v1 · #78338 · protein

Saposin-like protein na-slp-1

3S63: “Saposin-like protein na-slp-1”. X-ray diffraction, 1 pocket (best druggability 0.33). MolNFT v1 #78338 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
3S63
Type
protein
Length
178 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Saposin-like protein
Pockets
1 · best druggability 0.33

Structure

x-ray diffraction · 2 distinct chains · 63% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASaposin-like proteinprotein8865% helix, 0% strand—
BSaposin-like proteinprotein9062% helix, 0% strand—

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1550.330.7717empty

Interfaces

1 interface between chains.

  • A–B · 505 Ų buried · 8 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

  • 3S63 · Saposin-like protein Na-SLP-1 · the same entry in another collection · chain A against A, TM-score 1.00

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