MolNFT v1 · #7800 · protein

Solution structure of the lipoyl domain of the 2-oxoglutarate dehydrogenase complex from azotobacter vineland II, NMR, 25 structures

1GHK · E2, the dihydrolipoamide succinyltransferase component of…: “Solution structure of the lipoyl domain of the 2-oxoglutarate dehydrogenase complex from azotobacter vineland…”. Solution nmr, 1 pocket (best druggability 0.41). MolNFT v1…

PDB: 1GHK
Type: protein
Length: 79 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: E2, the dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase…
EC: 2.3.1.61
UniProt: P20708
Pockets: 1 · best druggability 0.41

Structure

solution nmr · 1 distinct chain · 0% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	E2, the dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61)	protein	79	0% helix, 34% strand	P20708

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.41	0.81	17	empty

Compared structures

1GHK · Solution structure of the lipoyl domain of the 2-oxoglutarate dehydrogenase complex from… · the same entry in another collection · chain A against A, TM-score 1.00
P20708 · AlphaFold monomer V2.0 prediction for dihydrolipoyllysine-residue succinyltransferase… · a predicted model of the same protein · chain A against A, TM-score 0.77

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P20708
Elsewhere: RCSB PDB 1GHK · PDBe 1GHK · UniProt P20708

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