MolNFT v1 · #77871 · protein

X-ray crystal structure of the vhs domain of human TOM1-like protein, northeast structural genomics consortium target HR3050E

3RRU · TOM1L1 protein: “X-ray crystal structure of the vhs domain of human TOM1-like protein, northeast structural genomics…”. X-ray diffraction, 1 pocket (best druggability 0.42). MolNFT v1 #77871 on GenesisL1: 3D structure, binding sites…

PDB: 3RRU
Type: protein
Length: 282 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: TOM1L1 protein
UniProt: Q8N749
Pockets: 1 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain · 74% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	TOM1L1 protein	protein	141	74% helix, 1% strand	Q8N749

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	163	0.42	0.74	30	empty

Interfaces

1 interface between chains.

A–B · 479 Å² buried · 6 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

3RRU · X-ray crystal structure of the VHS domain of human TOM1-like protein, Northeast… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8N749
Elsewhere: RCSB PDB 3RRU · PDBe 3RRU · UniProt Q8N749

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