MolNFT v1 · #77819 · protein
The crystal structure of a pathogenic protein from the xanthomonas campestris reveals a new tetrameric pilz domain self-assembled via a unusual helical bundle
3RQA · Putative uncharacterized protein: “The crystal structure of a pathogenic protein from the xanthomonas campestris reveals a new tetrameric pilz…”. X-ray diffraction, 8 pockets (best druggability 0.73). MolNFT v1 #77819 on GenesisL1…
- PDB
- 3RQA
- Type
- protein
- Length
- 691 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative uncharacterized protein
- UniProt
- B0RT03
- Pockets
- 8 · best druggability 0.73
Structure
x-ray diffraction · 4 distinct chains · 38% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative uncharacterized protein | protein | 175 | 38% helix, 27% strand | B0RT03 |
| B | Putative uncharacterized protein | protein | 168 | 36% helix, 26% strand | B0RT03 |
| C | Putative uncharacterized protein | protein | 179 | 40% helix, 27% strand | B0RT03 |
| D | Putative uncharacterized protein | protein | 169 | 39% helix, 29% strand | B0RT03 |
Ligands and binding sites
- ACT · Acetate ion · additive · 4 copies · chains A, D, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 884 | 0.73 | 0.77 | 74 | ACT |
| 2 | 810 | 0.72 | 0.78 | 83 | ACT |
| 3 | 409 | 0.65 | 0.78 | 49 | ACT |
| 4 | 383 | 0.63 | 0.78 | 46 | ACT |
| 5 | 110 | 0.56 | 0.83 | 20 | empty |
Interfaces
6 interfaces between chains.
- A–B · 1161 Ų buried · 17 hydrogen bonds · protein-protein
- A–D · 1102 Ų buried · 11 hydrogen bonds · protein-protein
- C–D · 1074 Ų buried · 15 hydrogen bonds · protein-protein
- B–C · 1017 Ų buried · 7 hydrogen bonds · protein-protein
- A–C · 71 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 3RQA · The Crystal Structure of a Pathogenic Protein from the Xanthomonas campestris Reveals a… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B0RT03
- Elsewhere: RCSB PDB 3RQA · PDBe 3RQA · UniProt B0RT03
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.