MolNFT v1 · #77562 · protein
Crystal structure of human gamma-tubulin complex protein 4 (GCP4)
3RIP · Gamma-tubulin complex component 4: “Crystal structure of human gamma-tubulin complex protein 4 (GCP4)”. X-ray diffraction, 3 pockets (best druggability 0.54). MolNFT v1 #77562 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 3RIP
- Type
- protein
- Length
- 568 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Gamma-tubulin complex component 4
- UniProt
- Q9UGJ1
- Pockets
- 3 · best druggability 0.54
Structure
x-ray diffraction · 1 distinct chain · 70% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Gamma-tubulin complex component 4 | protein | 568 | 70% helix, 4% strand | Q9UGJ1 |
Ligands and binding sites
- GOL · Glycerol · additive · 8 copies · chains A
- MRD · (4R)-2-methylpentane-2,4-diol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 130 | 0.54 | 0.82 | 29 | empty |
| 2 | 143 | 0.48 | 0.77 | 17 | empty |
| 3 | 85 | 0.39 | 0.77 | 13 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 3RIP · Crystal Structure of human gamma-tubulin complex protein 4 (GCP4) · the same entry in another collection · chain A against A, TM-score 1.00
- Q9UGJ1 · AlphaFold monomer V2.0 prediction for gamma-tubulin complex component 4 (Q9UGJ1) · a predicted model of the same protein · chain A against A, TM-score 0.86
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UGJ1
- Elsewhere: RCSB PDB 3RIP · PDBe 3RIP · UniProt Q9UGJ1
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