MolNFT v1 · #77515 · protein
Crystal structure of the holo form of glutaredoxin C5 from arabidopsis thaliana
3RHC · Glutaredoxin-C5, chloroplastic: “Crystal structure of the holo form of glutaredoxin C5 from arabidopsis thaliana”. X-ray diffraction, 2 ligands (GSH, FES), 1 pocket (best druggability 0.50). MolNFT v1 #77515 on GenesisL1: 3D…
- PDB
- 3RHC
- Type
- protein
- Length
- 203 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutaredoxin-C5, chloroplastic
- UniProt
- Q8GWS0
- Ligands
- GSH, FES
- Pockets
- 1 · best druggability 0.50
Structure
x-ray diffraction · 2 distinct chains · 53% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glutaredoxin-C5, chloroplastic | protein | 103 | 54% helix, 15% strand | Q8GWS0 |
| B | Glutaredoxin-C5, chloroplastic | protein | 100 | 52% helix, 17% strand | Q8GWS0 |
Ligands and binding sites
- GSH · Glutathione · ligand · 2 copies · chains A, B
- FES · Fe2/s2 (inorganic) cluster · ligand · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 110 | 0.50 | 0.81 | 17 | GSH, FES |
Interfaces
1 interface between chains.
- A–B · 193 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 3RHC · Crystal structure of the holo form of glutaredoxin C5 from Arabidopsis thaliana · the same entry in another collection · chain A against A, TM-score 1.00
- Q8GWS0 · AlphaFold monomer V2.0 prediction for glutaredoxin-C5, chloroplastic (Q8GWS0) · a predicted model of the same protein · chain B against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8GWS0
- Elsewhere: RCSB PDB 3RHC · PDBe 3RHC · UniProt Q8GWS0
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