MolNFT v1 · #77410 · protein
Copper (II) loaded bullfrog ferritin M chain
3RE7 · Ferritin, middle subunit: “Copper (II) loaded bullfrog ferritin M chain”. X-ray diffraction, 1 ligand (CU), 20 pockets (best druggability 0.81). MolNFT v1 #77410 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3RE7
- Type
- protein
- Length
- 4,128 residues
- Chains
- 24
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ferritin, middle subunit
- EC
- 1.16.3.1
- UniProt
- P07798
- Ligands
- CU
- Pockets
- 20 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 73% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | Ferritin, middle subunit (EC 1.16.3.1) | protein | 172 | 73% helix, 1% strand | P07798 |
Ligands and binding sites
- CU · Copper (II) ion · metal · 162 copies · chains A, J, O, R, G, X, B, H, I, E, V, C, S, D, K, Q, W, L, P, F, M, N, U, T
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 159 | 0.81 | 0.97 | 27 | empty |
| 2 | 142 | 0.81 | 0.97 | 25 | empty |
| 3 | 146 | 0.80 | 0.97 | 27 | empty |
| 4 | 140 | 0.80 | 0.97 | 30 | empty |
| 5 | 119 | 0.80 | 0.98 | 23 | empty |
Interfaces
72 interfaces between chains.
- M–S · 1606 Ų buried · 28 hydrogen bonds · protein-protein
- A–G · 1588 Ų buried · 36 hydrogen bonds · protein-protein
- N–R · 1588 Ų buried · 34 hydrogen bonds · protein-protein
- E–I · 1587 Ų buried · 29 hydrogen bonds · protein-protein
- L–V · 1587 Ų buried · 28 hydrogen bonds · protein-protein
Compared structures
- 3RE7 · Copper (II) loaded Bullfrog Ferritin M chain · the same entry in another collection · chain J against J, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07798
- Elsewhere: RCSB PDB 3RE7 · PDBe 3RE7 · UniProt P07798
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.