MolNFT v1 · #77378 · protein
Crystal structure of fumarate hydratase class II mycobacterium smegmatis
3RD8: “Crystal structure of fumarate hydratase class II mycobacterium smegmatis”. X-ray diffraction, 3 pockets (best druggability 0.40). MolNFT v1 #77378 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3RD8
- Type
- protein
- Length
- 457 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fumarate hydratase class II
- EC
- 4.2.1.2
- UniProt
- A0R2U8
- Pockets
- 3 · best druggability 0.40
Structure
x-ray diffraction · 1 distinct chain · 62% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fumarate hydratase class II (EC 4.2.1.2) | protein | 457 | 62% helix, 8% strand | A0R2U8 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 79 | 0.40 | 0.78 | 23 | empty |
| 2 | 59 | 0.30 | 0.75 | 13 | empty |
| 3 | 66 | 0.30 | 0.74 | 16 | empty |
Compared structures
- 3RD8 · Crystal structure of fumarate hydratase class II Mycobacterium smegmatis · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0R2U8
- Elsewhere: RCSB PDB 3RD8 · PDBe 3RD8 · UniProt A0R2U8
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