MolNFT v1 · #77106 · protein

Crystal structure of 4-aminobutyrate aminotransferase gabt from mycobacterium marinum covalently bound to pyridoxal phosphate

3R4T: “Crystal structure of 4-aminobutyrate aminotransferase gabt from mycobacterium marinum covalently bound to…”. X-ray diffraction, 2 ligands (NA, CL), 2 pockets (best druggability 0.56). MolNFT v1 #77106 on GenesisL1: 3D structure…

PDB: 3R4T
Type: protein
Length: 444 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 4-aminobutyrate aminotransferase gabt
UniProt: B2HN70
Ligands: NA, CL
Pockets: 2 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	4-aminobutyrate aminotransferase gabt	protein	444	41% helix, 17% strand	B2HN70

Ligands and binding sites

NA · Sodium ion · metal · chains A
CL · Chloride ion · ion · 4 copies · chains A
MPD · (4S)-2-methyl-2,4-pentanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	327	0.56	0.75	47	CL
2	147	0.46	0.77	27	empty

Modifications

Observed in the structure: 1 modified (cofactor).

Compared structures

3R4T · Crystal structure of 4-aminobutyrate aminotransferase GabT from Mycobacterium marinum… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B2HN70
Elsewhere: RCSB PDB 3R4T · PDBe 3R4T · UniProt B2HN70

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.