MolNFT v1 · #76922 · protein
Structure of the periplasmic stress response protein cpxp
3QZC · Periplasmic protein cpxp: “Structure of the periplasmic stress response protein cpxp”. X-ray diffraction, 1 ligand (ZN), 3 pockets (best druggability 0.70). MolNFT v1 #76922 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 3QZC
- Type
- protein
- Length
- 220 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Periplasmic protein cpxp
- UniProt
- P0AE85
- Ligands
- ZN
- Pockets
- 3 · best druggability 0.70
Structure
x-ray diffraction · 2 distinct chains · 71% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Periplasmic protein cpxp | protein | 108 | 76% helix, 0% strand | P0AE85 |
| B | Periplasmic protein cpxp | protein | 112 | 67% helix, 0% strand | P0AE85 |
Ligands and binding sites
- ZN · Zinc ion · metal · 9 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 459 | 0.70 | 0.81 | 43 | ZN |
| 2 | 193 | 0.52 | 0.77 | 29 | ZN |
| 3 | 58 | 0.29 | 0.74 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 1751 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0AE85
- Elsewhere: RCSB PDB 3QZC · PDBe 3QZC · UniProt P0AE85
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