MolNFT v1 · #76714 · protein
Analysis of a new family of widely distributed metal-independent alpha mannosidases provides unique insight into the processing of N-linked glycans, clostridium perfringens CPE0426 complexed with alpha-1,6- linked 1-thio-alpha-mannobiose
3QT9 · Putative uncharacterized protein CPE0426: “Analysis of a new family of widely distributed metal-independent alpha mannosidases provides unique insight…”. X-ray diffraction, 2 ligands (Z4Y, MAN), 3 pockets (best druggability 0.55).…
- PDB
- 3QT9
- Type
- protein
- Length
- 424 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative uncharacterized protein CPE0426
- UniProt
- Q8XNB2
- Ligands
- Z4Y, MAN
- Pockets
- 3 · best druggability 0.55
Structure
x-ray diffraction · 1 distinct chain · 49% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative uncharacterized protein CPE0426 | protein | 424 | 49% helix, 12% strand | Q8XNB2 |
Ligands and binding sites
- Z4Y · 6-thio-alpha-D-mannopyranose · ligand · chains A
- MAN · alpha-D-mannopyranose · sugar · chains A
- EDO · 1,2-ethanediol · additive · 6 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 126 | 0.55 | 0.82 | 23 | Z4Y, MAN |
| 2 | 111 | 0.40 | 0.75 | 17 | empty |
| 3 | 72 | 0.36 | 0.77 | 21 | empty |
Compared structures
- 3QT9 · Analysis of a new family of widely distributed metal-independent alpha mannosidases… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8XNB2
- Elsewhere: RCSB PDB 3QT9 · PDBe 3QT9 · UniProt Q8XNB2
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