MolNFT v1 · #76521 · protein

Candida albicans seryl-tRNA synthetase

3QNE · Seryl-tRNA synthetase, cytoplasmic: “Candida albicans seryl-tRNA synthetase”. X-ray diffraction, 5 pockets (best druggability 0.74). MolNFT v1 #76521 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3QNE
Type: protein
Length: 441 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Seryl-tRNA synthetase, cytoplasmic
EC: 6.1.1.11
UniProt: Q9HGT6
Pockets: 5 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 44% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Seryl-tRNA synthetase, cytoplasmic (EC 6.1.1.11)	protein	441	44% helix, 22% strand	Q9HGT6

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	519	0.74	0.82	51	empty
2	152	0.42	0.74	24	empty
3	50	0.31	0.77	15	empty
4	57	0.29	0.74	12	empty
5	51	0.26	0.73	21	empty

Compared structures

3QNE · Candida albicans seryl-tRNA synthetase · the same entry in another collection · chain A against A, TM-score 1.00
Q9HGT6 · AlphaFold monomer V2.0 prediction for serine--tRNA ligase, cytoplasmic (Q9HGT6) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9HGT6
Elsewhere: RCSB PDB 3QNE · PDBe 3QNE · UniProt Q9HGT6

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