MolNFT v1 · #76370 · protein

Recognition of the F&H motif by the lowe syndrome protein ocrl

3QIS · Inositol polyphosphate 5-phosphatase ocrl-1: “Recognition of the F&H motif by the lowe syndrome protein ocrl”. X-ray diffraction. MolNFT v1 #76370 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3QIS
Type: protein
Length: 306 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Inositol polyphosphate 5-phosphatase ocrl-1; Protein FAM109A
EC: 3.1.3.36
UniProt: Q01968, Q8N4B1

Structure

x-ray diffraction · 2 distinct chains · 41% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Inositol polyphosphate 5-phosphatase ocrl-1 (EC 3.1.3.36)	protein	293	40% helix, 20% strand	Q01968
B	Protein FAM109A	protein	13	62% helix, 0% strand	Q8N4B1

Interfaces

1 interface between chains.

A–B · 647 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

3QIS · Recognition of the F&H motif by the Lowe Syndrome protein OCRL · the same entry in another collection · chain A against A, TM-score 1.00
Q01968 · AlphaFold monomer V2.0 prediction for inositol polyphosphate 5-phosphatase ocrl (Q01968) · a predicted model of the same protein · chain A against A, TM-score 0.99
Q8N4B1 · AlphaFold monomer V2.0 prediction for sesquipedalian-1 (Q8N4B1) · a predicted model of the same protein · chain B against A, TM-score 0.65

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q01968
Every structure of UniProt Q8N4B1
Elsewhere: RCSB PDB 3QIS · PDBe 3QIS · UniProt Q01968 · UniProt Q8N4B1

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