MolNFT v1 · #76353 · protein

Crystal structure of a putative transcriptional regulator (YP_001089212.1) from clostridium difficile 630 at 1.86 a resolution

3QI7: “Crystal structure of a putative transcriptional regulator (YP_001089212.1) from clostridium difficile 630 at…”. X-ray diffraction, 4 pockets (best druggability 0.78). MolNFT v1 #76353 on GenesisL1: 3D structure, binding sites and…

PDB: 3QI7
Type: protein
Length: 714 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative transcriptional regulator
UniProt: Q183D5
Pockets: 4 · best druggability 0.78

Structure

x-ray diffraction · 2 distinct chains · 49% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative transcriptional regulator	protein	358	49% helix, 18% strand	Q183D5
B	Putative transcriptional regulator	protein	356	48% helix, 17% strand	Q183D5

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1116	0.78	0.80	89	empty
2	372	0.65	0.79	47	empty
3	363	0.62	0.78	41	empty
4	77	0.30	0.73	19	empty

Interfaces

1 interface between chains.

A–B · 607 Å² buried · 4 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 24 modified (engineered).

Compared structures

3QI7 · Crystal structure of a Putative transcriptional regulator (YP_001089212.1) from… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q183D5
Elsewhere: RCSB PDB 3QI7 · PDBe 3QI7 · UniProt Q183D5

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.