MolNFT v1 · #76225 · protein
Mouse pacsin 3 F-bar domain structure
3QE6 · Protein kinase C and casein kinase II substrate protein 3: “Mouse pacsin 3 F-bar domain structure”. X-ray diffraction, 1 ligand (MG), 2 pockets (best druggability 0.48). MolNFT v1 #76225 on GenesisL1: 3D structure, binding sites and…
- PDB
- 3QE6
- Type
- protein
- Length
- 569 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein kinase C and casein kinase II substrate protein 3
- UniProt
- Q99JB8
- Ligands
- MG
- Pockets
- 2 · best druggability 0.48
Structure
x-ray diffraction · 2 distinct chains · 78% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein kinase C and casein kinase II substrate protein 3 | protein | 283 | 78% helix, 0% strand | Q99JB8 |
| B | Protein kinase C and casein kinase II substrate protein 3 | protein | 286 | 78% helix, 0% strand | Q99JB8 |
Ligands and binding sites
- MG · Magnesium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 84 | 0.48 | 0.82 | 17 | empty |
| 2 | 82 | 0.44 | 0.80 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 4674 Ų buried · 54 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99JB8
- Elsewhere: RCSB PDB 3QE6 · PDBe 3QE6 · UniProt Q99JB8
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