MolNFT v1 · #75782 · protein + RNA
Crystal structure of the pumilio-homology domain from human PUMILIO1 in complex with P38ALPHA nrea
3Q0L · Pumilio homolog 1: “Crystal structure of the pumilio-homology domain from human PUMILIO1 in complex with P38ALPHA nrea”. X-ray diffraction. MolNFT v1 #75782 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3Q0L
- Type
- protein + RNA
- Length
- 697 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pumilio homolog 1; 5'-R(UP*GP*UP*AP*AP*AP*UP*A)-3'
- UniProt
- Q14671
Structure
x-ray diffraction · 3 distinct chains · 72% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pumilio homolog 1 | protein | 341 | 72% helix, 1% strand | Q14671 |
| B | Pumilio homolog 1 | protein | 340 | 72% helix, 1% strand | Q14671 |
| C, D | 5'-R(UP*GP*UP*AP*AP*AP*UP*A)-3' | rna | 8 | — | — |
Interfaces
2 interfaces between chains.
- B–D · 1399 Ų buried · 45 hydrogen bonds · protein-nucleic
- A–C · 1342 Ų buried · 42 hydrogen bonds · protein-nucleic
Compared structures
- 3Q0L · Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with… · the same entry in another collection · chain B against B, TM-score 1.00
- Q14671 · AlphaFold monomer V2.0 prediction for pumilio homolog 1 (Q14671) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q14671
- Elsewhere: RCSB PDB 3Q0L · PDBe 3Q0L · UniProt Q14671
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