MolNFT v1 · #75510 · protein

Crystal structure of the SPT6 core domain from saccharomyces cerevisiae, form SPT6(236-1259)

3PSF · Transcription elongation factor SPT6: “Crystal structure of the SPT6 core domain from saccharomyces cerevisiae, form SPT6(236-1259)”. X-ray diffraction, 15 pockets (best druggability 0.67). MolNFT v1 #75510 on GenesisL1: 3D…

PDB: 3PSF
Type: protein
Length: 826 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcription elongation factor SPT6
UniProt: P23615
Pockets: 15 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain · 59% helix, 6% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcription elongation factor SPT6	protein	826	59% helix, 6% strand	P23615

Pockets

15 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	447	0.67	0.79	35	empty
2	395	0.63	0.78	46	empty
3	183	0.59	0.81	29	empty
4	201	0.51	0.77	29	empty
5	54	0.46	0.84	13	empty

Compared structures

3PSF · Crystal Structure of the Spt6 core domain from Saccharomyces cerevisiae, Form… · the same entry in another collection · chain A against A, TM-score 1.00
P23615 · AlphaFold monomer V2.0 prediction for transcription elongation factor SPT6 (P23615) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P23615
Elsewhere: RCSB PDB 3PSF · PDBe 3PSF · UniProt P23615

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