MolNFT v1 · #75392 · protein

Porin conformation in the absence of calcium; refined structure at 2.5 ångströms resolution

3POR: “Porin conformation in the absence of calcium; refined structure at 2.5 ångströms resolution”. X-ray diffraction, 2 pockets (best druggability 0.53). MolNFT v1 #75392 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3POR
Type: protein
Length: 301 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Porin
UniProt: P31243
Pockets: 2 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 8% helix, 57% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Porin	protein	301	8% helix, 57% strand	P31243

Ligands and binding sites

C8E · (hydroxyethyloxy)tri(ethyloxy)octane · additive · chains A
TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	225	0.53	0.76	25	C8E
2	75	0.32	0.74	20	TRS

Compared structures

3POR · Porin conformation in the absence of calcium; refined structure at 2.5 ångströms… · the same entry in another collection · chain A against A, TM-score 1.00
P31243 · AlphaFold monomer V2.0 prediction for porin (P31243) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P31243
Elsewhere: RCSB PDB 3POR · PDBe 3POR · UniProt P31243

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