MolNFT v1 · #75283 · protein
Crystal structure of klebsiella pneumoniae udp-glucose 6-dehydrogenase complexed with udp-glucose
3PLN: “Crystal structure of klebsiella pneumoniae udp-glucose 6-dehydrogenase complexed with udp-glucose”. X-ray diffraction, 1 ligand (U5P), 3 pockets (best druggability 0.67). MolNFT v1 #75283 on GenesisL1: 3D structure, binding sites…
- PDB
- 3PLN
- Type
- protein
- Length
- 379 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Udp-glucose 6-dehydrogenase
- EC
- 1.1.1.22
- UniProt
- C4XAX5
- Ligands
- U5P
- Pockets
- 3 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Udp-glucose 6-dehydrogenase (EC 1.1.1.22) | protein | 379 | 46% helix, 15% strand | C4XAX5 |
Ligands and binding sites
- U5P · Uridine-5'-monophosphate · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 588 | 0.67 | 0.77 | 57 | U5P |
| 2 | 176 | 0.45 | 0.74 | 24 | empty |
| 3 | 75 | 0.35 | 0.76 | 18 | empty |
Compared structures
- 3PLN · Crystal structure of Klebsiella pneumoniae UDP-glucose 6-dehydrogenase complexed with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C4XAX5
- Elsewhere: RCSB PDB 3PLN · PDBe 3PLN · UniProt C4XAX5
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