MolNFT v1 · #75130 · protein
Clostridium thermocellum ribose-5-phosphate isomerase B with D-allose
3PH4: “Clostridium thermocellum ribose-5-phosphate isomerase B with D-allose”. X-ray diffraction, 1 ligand (AOS), 2 pockets (best druggability 0.60). MolNFT v1 #75130 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3PH4
- Type
- protein
- Length
- 296 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribose-5-phosphate isomerase
- UniProt
- A3DIL8
- Ligands
- AOS
- Pockets
- 2 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 50% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Ribose-5-phosphate isomerase | protein | 148 | 50% helix, 16% strand | A3DIL8 |
Ligands and binding sites
- AOS · D-allose · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 63 | 0.60 | 0.91 | 17 | AOS |
| 2 | 61 | 0.56 | 0.89 | 17 | AOS |
Interfaces
1 interface between chains.
- A–B · 2039 Ų buried · 25 hydrogen bonds · protein-protein
Compared structures
- 3PH4 · Clostridium thermocellum Ribose-5-Phosphate Isomerase B with d-allose · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A3DIL8
- Elsewhere: RCSB PDB 3PH4 · PDBe 3PH4 · UniProt A3DIL8
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