MolNFT v1 · #75126 · protein
Crystal structure of the heteromolecular chaperone, asce-ascg, from the type III secretion system in aeromonas hydrophila
3PH0: “Crystal structure of the heteromolecular chaperone, asce-ascg, from the type III secretion system in…”. X-ray diffraction, 3 pockets (best druggability 0.60). MolNFT v1 #75126 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 3PH0
- Type
- protein
- Length
- 226 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Asce; Ascg
- UniProt
- Q1EHA4, Q1EHA2
- Pockets
- 3 · best druggability 0.60
Structure
x-ray diffraction · 2 distinct chains · 81% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Asce | protein | 60 | 83% helix, 0% strand | Q1EHA4 |
| C, D | Ascg | protein | 53 | 77% helix, 0% strand | Q1EHA2 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 141 | 0.60 | 0.84 | 24 | empty |
| 2 | 131 | 0.57 | 0.83 | 26 | empty |
| 3 | 73 | 0.34 | 0.76 | 20 | empty |
Interfaces
6 interfaces between chains.
- A–C · 938 Ų buried · 2 hydrogen bonds · protein-protein
- B–D · 866 Ų buried · 3 hydrogen bonds · protein-protein
- C–D · 319 Ų buried · 0 hydrogen bonds · protein-protein
- C–B · 253 Ų buried · 2 hydrogen bonds · protein-protein
- A–B · 202 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 3PH0 · Crystal structure of the heteromolecular chaperone, AscE-AscG, from the type III… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q1EHA4
- Every structure of UniProt Q1EHA2
- Elsewhere: RCSB PDB 3PH0 · PDBe 3PH0 · UniProt Q1EHA4 · UniProt Q1EHA2
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