MolNFT v1 · #74905 · protein

M. jannaschii L7AE mutant

3PAF · 50S ribosomal protein L7AE: “M. jannaschii L7AE mutant”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.31). MolNFT v1 #74905 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3PAF
Type: protein
Length: 234 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 50S ribosomal protein L7AE
UniProt: P54066
Ligands: SO4
Pockets: 1 · best druggability 0.31

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	50S ribosomal protein L7AE	protein	117	48% helix, 16% strand	P54066

Ligands and binding sites

SO4 · Sulfate ion · ion · 2 copies · chains A
ACT · Acetate ion · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	69	0.31	0.74	18	empty

Interfaces

1 interface between chains.

A–B · 608 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

3PAF · M. jannaschii L7Ae mutant · the same entry in another collection · chain A against A, TM-score 1.00
P54066 · AlphaFold monomer V2.0 prediction for 50S ribosomal protein L7AE (P54066) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P54066
Elsewhere: RCSB PDB 3PAF · PDBe 3PAF · UniProt P54066

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