MolNFT v1 · #74785 · protein
Crystal structure of cytochrome P450CAM crystallized in the presence of a tethered substrate analog ADAC3-etg-boc
3P6W · Camphor 5-monooxygenase: “Crystal structure of cytochrome P450CAM crystallized in the presence of a tethered substrate analog…”. X-ray diffraction, 1 ligand (HEM), 2 pockets (best druggability 0.84). MolNFT v1 #74785 on GenesisL1…
- PDB
- 3P6W
- Type
- protein
- Length
- 400 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Camphor 5-monooxygenase
- EC
- 1.14.15.1
- UniProt
- P00183
- Ligands
- HEM
- Pockets
- 2 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 51% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Camphor 5-monooxygenase (EC 1.14.15.1) | protein | 400 | 51% helix, 11% strand | P00183 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 688 | 0.84 | 0.87 | 63 | HEM |
| 2 | 51 | 0.29 | 0.76 | 15 | empty |
Compared structures
- 3P6W · Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered… · the same entry in another collection · chain A against A, TM-score 1.00
- P00183 · AlphaFold monomer V2.0 prediction for camphor 5-monooxygenase (P00183) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00183
- Elsewhere: RCSB PDB 3P6W · PDBe 3P6W · UniProt P00183
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