MolNFT v1 · #74515 · protein
Ppar delta in complex with AZPPARD02
3OZ0 · Peroxisome proliferator-activated receptor delta: “Ppar delta in complex with AZPPARD02”. X-ray diffraction, 1 ligand (3OZ), 3 pockets (best druggability 0.81). MolNFT v1 #74515 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 3OZ0
- Type
- protein
- Length
- 260 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Peroxisome proliferator-activated receptor delta
- UniProt
- Q03181
- Ligands
- 3OZ
- Pockets
- 3 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 68% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Peroxisome proliferator-activated receptor delta | protein | 260 | 68% helix, 5% strand | Q03181 |
Ligands and binding sites
- 3OZ · [4-({(1S)-1-[(2,4-dichlorophenyl)carbamoyl]-1,3-dihydro-2H-isoindol-2-yl}methyl)-2-methylphenoxy]acetic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 513 | 0.81 | 0.87 | 57 | 3OZ |
| 2 | 65 | 0.36 | 0.78 | 12 | empty |
| 3 | 50 | 0.34 | 0.78 | 10 | empty |
Compared structures
- 3OZ0 · PPAR Delta in complex with azppard02 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q03181
- Elsewhere: RCSB PDB 3OZ0 · PDBe 3OZ0 · UniProt Q03181
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