MolNFT v1 · #74224 · protein
Ubiquitin-fold modifier 1 specific protease, UFSP2
3OQC · UFM1-specific protease 2: “Ubiquitin-fold modifier 1 specific protease, UFSP2”. X-ray diffraction, 8 pockets (best druggability 0.65). MolNFT v1 #74224 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3OQC
- Type
- protein
- Length
- 827 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- UFM1-specific protease 2
- EC
- 3.4.22.-
- UniProt
- Q99K23
- Pockets
- 8 · best druggability 0.65
Structure
x-ray diffraction · 2 distinct chains · 30% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | UFM1-specific protease 2 (EC 3.4.22.-) | protein | 416 | 31% helix, 25% strand | Q99K23 |
| B | UFM1-specific protease 2 (EC 3.4.22.-) | protein | 411 | 29% helix, 24% strand | Q99K23 |
Pockets
8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 593 | 0.65 | 0.76 | 63 | empty |
| 2 | 486 | 0.61 | 0.75 | 42 | empty |
| 3 | 172 | 0.48 | 0.76 | 28 | empty |
| 4 | 82 | 0.43 | 0.79 | 18 | empty |
| 5 | 167 | 0.41 | 0.73 | 28 | empty |
Interfaces
1 interface between chains.
- A–B · 29 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99K23
- Elsewhere: RCSB PDB 3OQC · PDBe 3OQC · UniProt Q99K23
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