MolNFT v1 · #74088 · protein

Crystal structure of a histidine triad family protein from entamoeba histolytica, bound to AMP

3OMF · Putative histidine triad family protein: “Crystal structure of a histidine triad family protein from entamoeba histolytica, bound to AMP”. X-ray diffraction, 2 ligands (AMP, ZN), 1 pocket (best druggability 0.28). MolNFT v1 #74088…

PDB: 3OMF
Type: protein
Length: 111 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative histidine triad family protein
UniProt: C4LYI2
Ligands: AMP, ZN
Pockets: 1 · best druggability 0.28

Structure

x-ray diffraction · 1 distinct chain · 24% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative histidine triad family protein	protein	111	24% helix, 23% strand	C4LYI2

Ligands and binding sites

AMP · Adenosine monophosphate · ligand · chains A
ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.28	0.74	18	AMP

Compared structures

3OMF · Crystal structure of a histidine triad family protein from Entamoeba histolytica, bound… · the same entry in another collection · chain A against A, TM-score 1.00
C4LYI2 · AlphaFold monomer V2.0 prediction for histidine triad nucleotide- binding protein (C4LYI2) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt C4LYI2
Elsewhere: RCSB PDB 3OMF · PDBe 3OMF · UniProt C4LYI2

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