MolNFT v1 · #73924 · protein
Protein structure of usp from L. major bound to uridine-5'- diphosphate-galactose
3OH2 · Udp-sugar pyrophosphorylase: “Protein structure of usp from L. major bound to uridine-5'- diphosphate-galactose”. X-ray diffraction, 1 ligand (GDU), 5 pockets (best druggability 0.79). MolNFT v1 #73924 on GenesisL1: 3D structure…
- PDB
- 3OH2
- Type
- protein
- Length
- 579 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Udp-sugar pyrophosphorylase
- EC
- 2.7.7.64
- UniProt
- D3G6S4
- Ligands
- GDU
- Pockets
- 5 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 34% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Udp-sugar pyrophosphorylase (EC 2.7.7.64) | protein | 579 | 34% helix, 23% strand | D3G6S4 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 935 | 0.79 | 0.81 | 75 | GDU |
| 2 | 295 | 0.70 | 0.84 | 41 | empty |
| 3 | 121 | 0.53 | 0.82 | 24 | empty |
| 4 | 230 | 0.49 | 0.74 | 27 | empty |
| 5 | 52 | 0.25 | 0.73 | 12 | empty |
Compared structures
- 3OH2 · Protein structure of USP from L. major bound to URIDINE-5'-DIPHOSPHATE-GALACTOSE · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D3G6S4
- Elsewhere: RCSB PDB 3OH2 · PDBe 3OH2 · UniProt D3G6S4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.