MolNFT v1 · #73921 · protein

Protein structure of usp from L. major in apo-form

3OGZ · Udp-sugar pyrophosphorylase: “Protein structure of usp from L. major in apo-form”. X-ray diffraction, 6 pockets (best druggability 0.70). MolNFT v1 #73921 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3OGZ
Type: protein
Length: 578 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Udp-sugar pyrophosphorylase
EC: 2.7.7.64
UniProt: D3G6S4
Pockets: 6 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Udp-sugar pyrophosphorylase (EC 2.7.7.64)	protein	578	34% helix, 23% strand	D3G6S4

Ligands and binding sites

GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	336	0.70	0.83	50	empty
2	517	0.64	0.76	43	empty
3	372	0.60	0.76	31	empty
4	237	0.49	0.74	26	empty
5	109	0.47	0.79	26	empty

Compared structures

3OGZ · Protein structure of USP from L. major in Apo-form · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D3G6S4
Elsewhere: RCSB PDB 3OGZ · PDBe 3OGZ · UniProt D3G6S4

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