MolNFT v1 · #7390 · protein

Amylosucrase from neisseria polysaccharea

1G5A: “Amylosucrase from neisseria polysaccharea”. X-ray diffraction, 1 ligand (NA), 5 pockets (best druggability 0.76). MolNFT v1 #7390 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1G5A
Type: protein
Length: 628 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Amylosucrase
EC: 2.4.1.4
UniProt: Q9ZEU2
Ligands: NA
Pockets: 5 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Amylosucrase (EC 2.4.1.4)	protein	628	42% helix, 15% strand	Q9ZEU2

Ligands and binding sites

NA · Sodium ion · metal · chains A
TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A
EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	460	0.76	0.85	54	TRS, EPE
2	203	0.58	0.80	32	empty
3	65	0.39	0.80	15	empty
4	59	0.26	0.73	12	empty
5	50	0.25	0.73	14	empty

Compared structures

1G5A · Amylosucrase from neisseria polysaccharea · the same entry in another collection · chain A against A, TM-score 1.00
Q9ZEU2 · AlphaFold monomer V2.0 prediction for amylosucrase (Q9ZEU2) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9ZEU2
Elsewhere: RCSB PDB 1G5A · PDBe 1G5A · UniProt Q9ZEU2

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