MolNFT v1 · #73797 · protein

Structure of recombinant haemophilus influenzae E(P4) acid phosphatase complexed with the inhibitor adenosine 5-O-thiomonophosphate

3OCZ · Lipoprotein E: “Structure of recombinant haemophilus influenzae E(P4) acid phosphatase complexed with the inhibitor adenosine…”. X-ray diffraction, 2 ligands (SRA, MG), 2 pockets (best druggability 0.72). MolNFT v1 #73797 on…

PDB: 3OCZ
Type: protein
Length: 247 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lipoprotein E
EC: 3.1.3.2
UniProt: P26093
Ligands: SRA, MG
Pockets: 2 · best druggability 0.72

Structure

x-ray diffraction · 1 distinct chain · 51% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lipoprotein E (EC 3.1.3.2)	protein	247	51% helix, 15% strand	P26093

Ligands and binding sites

SRA · Adenosine -5'-thio-monophosphate · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	511	0.72	0.81	57	MG, SRA
2	88	0.32	0.73	17	empty

Compared structures

3OCZ · Structure of Recombinant Haemophilus influenzae e(P4) Acid Phosphatase Complexed with the… · the same entry in another collection · chain A against A, TM-score 1.00
P26093 · AlphaFold monomer V2.0 prediction for lipoprotein E (P26093) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P26093
Elsewhere: RCSB PDB 3OCZ · PDBe 3OCZ · UniProt P26093

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