MolNFT v1 · #73772 · protein
Crystal structure of putative udp-N-acetylglucosamine pyrophosphorylase from entamoeba histolytica
3OC9: “Crystal structure of putative udp-N-acetylglucosamine pyrophosphorylase from entamoeba histolytica”. X-ray diffraction, 1 ligand (SO4), 3 pockets (best druggability 0.71). MolNFT v1 #73772 on GenesisL1: 3D structure, binding sites…
- PDB
- 3OC9
- Type
- protein
- Length
- 400 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Udp-N-acetylglucosamine pyrophosphorylase
- EC
- 2.7.7.23
- UniProt
- C4M036
- Ligands
- SO4
- Pockets
- 3 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 31% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Udp-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) | protein | 400 | 31% helix, 26% strand | C4M036 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 754 | 0.71 | 0.77 | 62 | EDO |
| 2 | 173 | 0.47 | 0.76 | 21 | empty |
| 3 | 78 | 0.33 | 0.75 | 18 | empty |
Compared structures
- 3OC9 · Crystal structure of putative UDP-N-acetylglucosamine pyrophosphorylase from Entamoeba… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C4M036
- Elsewhere: RCSB PDB 3OC9 · PDBe 3OC9 · UniProt C4M036
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