MolNFT v1 · #73737 · protein
Mbp-fusion protein of the major peanut allergen ara H 2
3OB4 · Maltose ABC transporter periplasmic PROTEIN,ARAH 2: “Mbp-fusion protein of the major peanut allergen ara H 2”. X-ray diffraction, 3 ligands (GLC, CL, SO4), 5 pockets (best druggability 0.74). MolNFT v1 #73737 on GenesisL1: 3D…
- PDB
- 3OB4
- Type
- protein
- Length
- 474 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Maltose ABC transporter periplasmic PROTEIN,ARAH 2
- UniProt
- D8A942, A0A445BYI5
- Ligands
- GLC, CL, SO4
- Pockets
- 5 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 49% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Maltose ABC transporter periplasmic PROTEIN,ARAH 2 | protein | 474 | 49% helix, 16% strand | D8A942, A0A445BYI5 |
Ligands and binding sites
- GLC · alpha-D-glucopyranose · sugar · 3 copies · chains A
- CL · Chloride ion · ion · 5 copies · chains A
- SO4 · Sulfate ion · ion · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 545 | 0.74 | 0.81 | 51 | GLC |
| 2 | 86 | 0.41 | 0.78 | 17 | empty |
| 3 | 88 | 0.40 | 0.77 | 16 | CL |
| 4 | 88 | 0.33 | 0.73 | 16 | empty |
| 5 | 55 | 0.29 | 0.75 | 13 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 3OB4 · MBP-fusion protein of the major peanut allergen Ara h 2 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D8A942
- Every structure of UniProt A0A445BYI5
- Elsewhere: RCSB PDB 3OB4 · PDBe 3OB4 · UniProt D8A942 · UniProt A0A445BYI5
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