MolNFT v1 · #73618 · protein

Crystal structure of archaeoglobus fulgidus NEP1 bound to S- adenosylhomocysteine

3O7B · Ribosome biogenesis NEP1 RNA methyltransferase: “Crystal structure of archaeoglobus fulgidus NEP1 bound to S- adenosylhomocysteine”. X-ray diffraction, 2 ligands (TYR, SAH), 1 pocket (best druggability 0.61). MolNFT v1 #73618 on…

PDB: 3O7B
Type: protein
Length: 216 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ribosome biogenesis NEP1 RNA methyltransferase
UniProt: O29524
Ligands: TYR, SAH
Pockets: 1 · best druggability 0.61

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ribosome biogenesis NEP1 RNA methyltransferase	protein	216	38% helix, 24% strand	O29524

Ligands and binding sites

TYR · Tyrosine · ligand · chains A
SAH · S-adenosyl-L-homocysteine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	204	0.61	0.82	28	SAH

Compared structures

3O7B · Crystal structure of Archaeoglobus Fulgidus Nep1 bound to S-adenosylhomocysteine · the same entry in another collection · chain A against A, TM-score 1.00
O29524 · AlphaFold monomer V2.0 prediction for ribosomal RNA small subunit methyltransferase NEP1… · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O29524
Elsewhere: RCSB PDB 3O7B · PDBe 3O7B · UniProt O29524

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.