MolNFT v1 · #73595 · protein
Crystal structure of APL1 leucine-rich repeat domain
3O6N: “Crystal structure of APL1 leucine-rich repeat domain”. X-ray diffraction, 1 ligand (NAG), 1 pocket (best druggability 0.31). MolNFT v1 #73595 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3O6N
- Type
- protein
- Length
- 378 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- APL1
- Ligands
- NAG
- Pockets
- 1 · best druggability 0.31
Structure
x-ray diffraction · 1 distinct chain · 9% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | APL1 | protein | 378 | 9% helix, 22% strand | — |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.31 | 0.77 | 14 | empty |
Modifications
Observed in the structure: 3 disulfide, 3 glycan (disulfide, N-glycosylation).
Compared structures
- 3O6N · Crystal Structure of APL1 leucine-rich repeat domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 3O6N · PDBe 3O6N
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