MolNFT v1 · #73160 · protein
Structural insights of adeno-associated virus 5. a gene therapy vector for cystic fibrosis
3NTT · Capsid protein: “Structural insights of adeno-associated virus 5. a gene therapy vector for cystic fibrosis”. X-ray diffraction, 1 ligand (NA), 4 pockets (best druggability 0.68). MolNFT v1 #73160 on GenesisL1: 3D structure, binding…
- PDB
- 3NTT
- Type
- protein
- Length
- 516 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Capsid protein
- UniProt
- Q9YIJ1
- Ligands
- NA
- Pockets
- 4 · best druggability 0.68
Structure
x-ray diffraction · 1 distinct chain · 7% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Capsid protein | protein | 516 | 7% helix, 33% strand | Q9YIJ1 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 625 | 0.68 | 0.77 | 61 | GOL |
| 2 | 330 | 0.54 | 0.74 | 44 | empty |
| 3 | 142 | 0.49 | 0.78 | 25 | empty |
| 4 | 173 | 0.44 | 0.74 | 25 | empty |
Compared structures
- 3NTT · Structural insights of Adeno-Associated virus 5. A gene therapy Vector for Cystic Fibrosis · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9YIJ1
- Elsewhere: RCSB PDB 3NTT · PDBe 3NTT · UniProt Q9YIJ1
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