MolNFT v1 · #73105 · protein
Crystal structure of hte RNA recognition motif of yeast EIF3B residues 76-170
3NS6 · Eukaryotic translation initiation factor 3 subunit B: “Crystal structure of hte RNA recognition motif of yeast EIF3B residues 76-170”. X-ray diffraction, 1 ligand (SO4), 3 pockets (best druggability 0.44). MolNFT v1 #73105 on…
- PDB
- 3NS6
- Type
- protein
- Length
- 198 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Eukaryotic translation initiation factor 3 subunit B
- UniProt
- P06103
- Ligands
- SO4
- Pockets
- 3 · best druggability 0.44
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Eukaryotic translation initiation factor 3 subunit B | protein | 99 | 38% helix, 27% strand | P06103 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 172 | 0.44 | 0.74 | 26 | empty |
| 2 | 146 | 0.44 | 0.75 | 20 | empty |
| 3 | 53 | 0.25 | 0.73 | 22 | SO4 |
Interfaces
1 interface between chains.
- A–B · 985 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 3NS6 · Crystal structure of hte RNA recognition motif of yeast eIF3b residues 76-170 · the same entry in another collection · chain A against A, TM-score 1.00
- P06103 · AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 3 subunit… · a predicted model of the same protein · chain B against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06103
- Elsewhere: RCSB PDB 3NS6 · PDBe 3NS6 · UniProt P06103
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