MolNFT v1 · #72969 · protein

Crystal structure of the phr domain from human BTBD2 protein

3NO8 · BTB/POZ domain-containing protein 2: “Crystal structure of the phr domain from human BTBD2 protein”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.52). MolNFT v1 #72969 on GenesisL1: 3D structure, binding sites…

PDB: 3NO8
Type: protein
Length: 314 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: BTB/POZ domain-containing protein 2
UniProt: Q9BX70
Ligands: SO4
Pockets: 1 · best druggability 0.52

Structure

x-ray diffraction · 1 distinct chain · 0% helix, 60% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	BTB/POZ domain-containing protein 2	protein	157	0% helix, 60% strand	Q9BX70

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A
GOL · Glycerol · additive · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	281	0.52	0.75	36	empty

Interfaces

1 interface between chains.

A–B · 443 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

3NO8 · Crystal structure of the PHR domain from human BTBD2 Protein · the same entry in another collection · chain A against A, TM-score 1.00
Q9BX70 · AlphaFold monomer V2.0 prediction for BTB/POZ domain-containing protein 2 (Q9BX70) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9BX70
Elsewhere: RCSB PDB 3NO8 · PDBe 3NO8 · UniProt Q9BX70

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