MolNFT v1 · #72940 · protein
The crystal structure of ABC transporter from rhodopseudomonas palustris
3NND · Possible substrate binding protein of ABC transporter system: “The crystal structure of ABC transporter from rhodopseudomonas palustris”. X-ray diffraction, 20 pockets (best druggability 0.76). MolNFT v1 #72940 on GenesisL1: 3D…
- PDB
- 3NND
- Type
- protein
- Length
- 1,326 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Possible substrate binding protein of ABC transporter system
- UniProt
- Q6N1K8
- Pockets
- 20 · best druggability 0.76
Structure
x-ray diffraction · 4 distinct chains · 42% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Possible substrate binding protein of ABC transporter system | protein | 330 | 42% helix, 22% strand | Q6N1K8 |
| A | Possible substrate binding protein of ABC transporter system | protein | 339 | 41% helix, 24% strand | Q6N1K8 |
| C | Possible substrate binding protein of ABC transporter system | protein | 329 | 42% helix, 24% strand | Q6N1K8 |
| D | Possible substrate binding protein of ABC transporter system | protein | 328 | 44% helix, 25% strand | Q6N1K8 |
Pockets
20 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1001 | 0.76 | 0.78 | 104 | empty |
| 2 | 646 | 0.75 | 0.81 | 98 | empty |
| 3 | 529 | 0.69 | 0.79 | 57 | empty |
| 4 | 324 | 0.69 | 0.82 | 57 | empty |
| 5 | 553 | 0.68 | 0.78 | 59 | empty |
Interfaces
6 interfaces between chains.
- B–A · 2914 Ų buried · 30 hydrogen bonds · protein-protein
- C–D · 2814 Ų buried · 37 hydrogen bonds · protein-protein
- B–C · 912 Ų buried · 12 hydrogen bonds · protein-protein
- A–D · 888 Ų buried · 10 hydrogen bonds · protein-protein
- A–C · 814 Ų buried · 9 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 40 modified (engineered).
Compared structures
- 3NND · The crystal structure of ABC transporter from Rhodopseudomonas palustris · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6N1K8
- Elsewhere: RCSB PDB 3NND · PDBe 3NND · UniProt Q6N1K8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.