MolNFT v1 · #72683 · protein

Crystal structure of an alginate lyase (BACOVA_01668) from bacteroides ovatus at 1.95 a resolution

3NFV: “Crystal structure of an alginate lyase (BACOVA_01668) from bacteroides ovatus at 1.95 a resolution”. X-ray diffraction, 3 pockets (best druggability 0.74). MolNFT v1 #72683 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 3NFV
Type: protein
Length: 382 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Alginate lyase
UniProt: A7LV19
Pockets: 3 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 58% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Alginate lyase	protein	382	58% helix, 4% strand	A7LV19

Ligands and binding sites

EDO · 1,2-ethanediol · additive · 13 copies · chains A
IPA · Isopropyl alcohol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	990	0.74	0.77	62	IPA, EDO
2	71	0.38	0.78	16	empty
3	63	0.37	0.78	19	IPA

Modifications

Observed in the structure: 17 modified (engineered).

Compared structures

3NFV · Crystal structure of an alginate lyase (BACOVA_01668) from Bacteroides ovatus at 1.95 A… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A7LV19
Elsewhere: RCSB PDB 3NFV · PDBe 3NFV · UniProt A7LV19

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