MolNFT v1 · #71597 · protein
Crystal structure of a putative transcriptional regulator protein, lacl family from rhizobium etli
3MIZ · Putative transcriptional regulator protein, laci family: “Crystal structure of a putative transcriptional regulator protein, lacl family from rhizobium etli”. X-ray diffraction, 8 pockets (best druggability 0.77). MolNFT v1 #71597…
- PDB
- 3MIZ
- Type
- protein
- Length
- 562 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative transcriptional regulator protein, laci family
- UniProt
- Q2K0Z9
- Pockets
- 8 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 37% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative transcriptional regulator protein, laci family | protein | 281 | 37% helix, 24% strand | Q2K0Z9 |
| B | Putative transcriptional regulator protein, laci family | protein | 281 | 37% helix, 24% strand | Q2K0Z9 |
Pockets
8 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 133 | 0.77 | 0.96 | 21 | empty |
| 2 | 218 | 0.72 | 0.88 | 40 | empty |
| 3 | 72 | 0.67 | 0.94 | 22 | empty |
| 4 | 247 | 0.66 | 0.83 | 52 | empty |
| 5 | 51 | 0.63 | 0.95 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 1322 Ų buried · 19 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 18 modified (engineered).
Compared structures
- 3MIZ · Crystal structure of a putative transcriptional regulator protein, Lacl family from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2K0Z9
- Elsewhere: RCSB PDB 3MIZ · PDBe 3MIZ · UniProt Q2K0Z9
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