MolNFT v1 · #71541 · protein
Crystal structure of lprg mutant V91W from mycobacterium tuberculosis
3MH9 · Lipoprotein lprg: “Crystal structure of lprg mutant V91W from mycobacterium tuberculosis”. X-ray diffraction, 3 pockets (best druggability 0.80). MolNFT v1 #71541 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3MH9
- Type
- protein
- Length
- 410 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lipoprotein lprg
- UniProt
- P0A5I8
- Pockets
- 3 · best druggability 0.80
Structure
x-ray diffraction · 2 distinct chains · 18% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C | Lipoprotein lprg | protein | 205 | 18% helix, 48% strand | P0A5I8 |
| A | Lipoprotein lprg | protein | 205 | 19% helix, 48% strand | P0A5I8 |
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 421 | 0.80 | 0.87 | 46 | empty |
| 2 | 394 | 0.78 | 0.87 | 40 | empty |
| 3 | 79 | 0.53 | 0.85 | 24 | empty |
Interfaces
1 interface between chains.
- C–A · 395 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 3MH9 · Crystal structure of LprG mutant V91W from Mycobacterium tuberculosis · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A5I8
- Elsewhere: RCSB PDB 3MH9 · PDBe 3MH9 · UniProt P0A5I8
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