MolNFT v1 · #71484 · protein
Crystal structures and mutational analyses of acyl-CoA carboxylase subunit of streptomyces coelicolor
3MFM · Propionyl-CoA carboxylase complex B subunit: “Crystal structures and mutational analyses of acyl-CoA carboxylase subunit of streptomyces coelicolor”. X-ray diffraction, 20 pockets (best druggability 0.83). MolNFT v1 #71484 on…
- PDB
- 3MFM
- Type
- protein
- Length
- 3,126 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Propionyl-CoA carboxylase complex B subunit
- UniProt
- Q9X4K7
- Pockets
- 20 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C, F, A, B, D, E | Propionyl-CoA carboxylase complex B subunit | protein | 521 | 41% helix, 19% strand | Q9X4K7 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1100 | 0.83 | 0.84 | 98 | empty |
| 2 | 1111 | 0.83 | 0.84 | 109 | empty |
| 3 | 1117 | 0.83 | 0.84 | 96 | empty |
| 4 | 815 | 0.73 | 0.78 | 78 | empty |
| 5 | 534 | 0.73 | 0.82 | 74 | empty |
Interfaces
15 interfaces between chains.
- A–B · 4772 Ų buried · 63 hydrogen bonds · protein-protein
- C–F · 4746 Ų buried · 66 hydrogen bonds · protein-protein
- D–E · 4681 Ų buried · 65 hydrogen bonds · protein-protein
- B–E · 1473 Ų buried · 23 hydrogen bonds · protein-protein
- F–B · 1461 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 3MFM · Crystal Structures and Mutational Analyses of Acyl-CoA Carboxylase Subunit of… · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9X4K7
- Elsewhere: RCSB PDB 3MFM · PDBe 3MFM · UniProt Q9X4K7
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