MolNFT v1 · #71411 · protein

Structure of stringent starvation protein a (sspa) from pseudomonas putida

3MDK: “Structure of stringent starvation protein a (sspa) from pseudomonas putida”. X-ray diffraction, 4 pockets (best druggability 0.68). MolNFT v1 #71411 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3MDK
Type: protein
Length: 406 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Stringent starvation protein a
UniProt: Q88N92
Pockets: 4 · best druggability 0.68

Structure

x-ray diffraction · 2 distinct chains · 56% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Stringent starvation protein a	protein	200	57% helix, 11% strand	Q88N92
B	Stringent starvation protein a	protein	206	55% helix, 9% strand	Q88N92

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	488	0.68	0.79	47	empty
2	129	0.41	0.75	27	empty
3	110	0.40	0.76	26	empty
4	77	0.29	0.72	13	empty

Interfaces

1 interface between chains.

A–B · 1158 Å² buried · 14 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 12 modified (engineered).

Compared structures

3MDK · Structure of stringent starvation protein A (sspA) from Pseudomonas putida · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q88N92
Elsewhere: RCSB PDB 3MDK · PDBe 3MDK · UniProt Q88N92

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