MolNFT v1 · #70834 · protein

The crystal structure of MPP8

3LWE · M-phase phosphoprotein 8: “The crystal structure of MPP8”. X-ray diffraction, 1 pocket (best druggability 0.36). MolNFT v1 #70834 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3LWE
Type: protein
Length: 120 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: M-phase phosphoprotein 8
UniProt: Q99549
Pockets: 1 · best druggability 0.36

Structure

x-ray diffraction · 2 distinct chains · 35% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	M-phase phosphoprotein 8	protein	61	36% helix, 36% strand	Q99549
B	M-phase phosphoprotein 8	protein	59	34% helix, 37% strand	Q99549

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	93	0.36	0.74	13	empty

Interfaces

1 interface between chains.

A–B · 636 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

3LWE · The crystal structure of MPP8 · the same entry in another collection · chain A against A, TM-score 1.00
Q99549 · AlphaFold monomer V2.0 prediction for M-phase phosphoprotein 8 (Q99549) · a predicted model of the same protein · chain A against A, TM-score 0.81

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q99549
Elsewhere: RCSB PDB 3LWE · PDBe 3LWE · UniProt Q99549

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