MolNFT v1 · #70829 · protein

Structure of a cytoplasmic domain of salmonella inva

3LW9 · Invasion protein inva: “Structure of a cytoplasmic domain of salmonella inva”. X-ray diffraction, 3 pockets (best druggability 0.46). MolNFT v1 #70829 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3LW9
Type: protein
Length: 333 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Invasion protein inva
UniProt: P0A1I3
Pockets: 3 · best druggability 0.46

Structure

x-ray diffraction · 2 distinct chains · 45% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Invasion protein inva	protein	166	44% helix, 24% strand	P0A1I3
B	Invasion protein inva	protein	167	46% helix, 22% strand	P0A1I3

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	86	0.46	0.81	15	empty
2	68	0.41	0.80	15	empty
3	82	0.35	0.74	15	empty

Modifications

Observed in the structure: 8 modified (engineered).

Compared structures

3LW9 · Structure of a Cytoplasmic Domain of Salmonella InvA · the same entry in another collection · chain A against A, TM-score 1.00
P0A1I3 · AlphaFold monomer V2.0 prediction for invasion protein inva (P0A1I3) · a predicted model of the same protein · chain A against A, TM-score 0.80

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A1I3
Elsewhere: RCSB PDB 3LW9 · PDBe 3LW9 · UniProt P0A1I3

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