MolNFT v1 · #70716 · protein
Crystal structure of putative membrane anchored protein from corynebacterium diphtheriae
3LSO: “Crystal structure of putative membrane anchored protein from corynebacterium diphtheriae”. X-ray diffraction, 1 ligand (CL), 8 pockets (best druggability 0.80). MolNFT v1 #70716 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 3LSO
- Type
- protein
- Length
- 890 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative membrane anchored protein
- UniProt
- Q6NEZ3
- Ligands
- CL
- Pockets
- 8 · best druggability 0.80
Structure
x-ray diffraction · 1 distinct chain · 1% helix, 53% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Putative membrane anchored protein | protein | 445 | 1% helix, 53% strand | Q6NEZ3 |
Ligands and binding sites
- CL · Chloride ion · ion · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 230 | 0.80 | 0.93 | 35 | empty |
| 2 | 253 | 0.80 | 0.92 | 38 | empty |
| 3 | 167 | 0.52 | 0.79 | 25 | empty |
| 4 | 281 | 0.52 | 0.75 | 34 | empty |
| 5 | 146 | 0.50 | 0.79 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 192 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 12 modified, 2 disulfide (engineered, disulfide, methylation).
Compared structures
- 3LSO · Crystal structure of Putative membrane anchored protein from Corynebacterium diphtheriae · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6NEZ3
- Elsewhere: RCSB PDB 3LSO · PDBe 3LSO · UniProt Q6NEZ3
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