MolNFT v1 · #70612 · protein

Crystal structure of putative methyltransferase small domain protein from listeria monocytogenes

3LPM: “Crystal structure of putative methyltransferase small domain protein from listeria monocytogenes”. X-ray diffraction, 6 pockets (best druggability 0.51). MolNFT v1 #70612 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3LPM
Type: protein
Length: 444 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative methyltransferase
UniProt: C1KXY4
Pockets: 6 · best druggability 0.51

Structure

x-ray diffraction · 1 distinct chain · 30% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Putative methyltransferase	protein	222	30% helix, 31% strand	C1KXY4

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	248	0.51	0.75	36	empty
2	162	0.49	0.77	35	empty
3	119	0.45	0.78	30	empty
4	52	0.34	0.78	12	empty
5	54	0.32	0.77	16	empty

Interfaces

1 interface between chains.

A–B · 870 Å² buried · 2 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 modified (engineered).

Compared structures

3LPM · Crystal structure of putative methyltransferase small domain protein from Listeria… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt C1KXY4
Elsewhere: RCSB PDB 3LPM · PDBe 3LPM · UniProt C1KXY4

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.