MolNFT v1 · #70282 · protein
Ctd of tarocystatin in complex with papain
3LFY: “Ctd of tarocystatin in complex with papain”. X-ray diffraction, 2 pockets (best druggability 0.46). MolNFT v1 #70282 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3LFY
- Type
- protein
- Length
- 429 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Papain
- EC
- 3.4.22.2
- UniProt
- P00784
- Pockets
- 2 · best druggability 0.46
Structure
x-ray diffraction · 2 distinct chains · 24% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Papain (EC 3.4.22.2) | protein | 214 | 24% helix, 20% strand | P00784 |
| C | Papain (EC 3.4.22.2) | protein | 215 | 25% helix, 20% strand | P00784 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 216 | 0.46 | 0.73 | 36 | empty |
| 2 | 120 | 0.38 | 0.74 | 26 | empty |
Interfaces
1 interface between chains.
- A–C · 726 Ų buried · 15 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide, 2 modified (disulfide, oxidation).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00784
- Elsewhere: RCSB PDB 3LFY · PDBe 3LFY · UniProt P00784
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