MolNFT v1 · #70269 · protein

Crystal structure of manxb from thermoanaerobacter tengcongensis

3LFJ · Phosphotransferase system, MANNOSE/FRUCTOSE/N…: “Crystal structure of manxb from thermoanaerobacter tengcongensis”. X-ray diffraction, 1 pocket (best druggability 0.54). MolNFT v1 #70269 on GenesisL1: 3D structure, binding sites and…

PDB: 3LFJ
Type: protein
Length: 333 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phosphotransferase system, MANNOSE/FRUCTOSE/N- acetylgalactosamine-specific component iib
UniProt: Q8RD54
Pockets: 1 · best druggability 0.54

Structure

x-ray diffraction · 2 distinct chains · 36% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phosphotransferase system, MANNOSE/FRUCTOSE/N- acetylgalactosamine-specific component iib	protein	167	36% helix, 27% strand	Q8RD54
B	Phosphotransferase system, MANNOSE/FRUCTOSE/N- acetylgalactosamine-specific component iib	protein	166	36% helix, 27% strand	Q8RD54

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	332	0.54	0.74	39	empty

Interfaces

1 interface between chains.

A–B · 163 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

3LFJ · Crystal structure of manxB from Thermoanaerobacter tengcongensis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8RD54
Elsewhere: RCSB PDB 3LFJ · PDBe 3LFJ · UniProt Q8RD54

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